Geraint Thomas Bio

Articles

Illustrative render of a large pink and mauve protein mass splitting into smaller fragments along a glowing seam, among fine dark filaments.

Filaggrin: The Ultimate Sacrifice

Follow filaggrin through four acts, from a giant precursor stored in liquid-like granules to the small molecules its breakdown releases to hold water and acidify the surface.

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Scratch the surface.

Foundations · Start here

Under the skin.

Mechanisms

Down the rabbit hole.

Deep dives

All articles

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barrier biology

barrier damage & repair

irritation & reactivity

skincare logic

environmental stressors

TITLE

TOPIC

READING TIME

A Dance with the Devil

min read: 19 mins

A Question of Fate

min read: 15 mins

Phospholipase A₂: Breaking Ground

min read: 20 mins

NHE1: Preparing the Ground

min read: 14 mins

Filaggrin: The Ultimate Sacrifice

min read: 23 mins

Hard Water and What Survives the Rinse

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min read: 14 mins

The Ingredient Worked in Cells. Does That Mean It Works on Skin?

min read: 11 mins

How Does Skin Know Its Barrier Has Been Damaged?

min read: 12 mins

When Does Urea Stop Being a Moisturiser?

min read: 9 mins

Why Does Skin Feel Tight After Cleansing?

min read: 5 mins

Is the Stratum Corneum Dead?

min read: 8 mins

Does Stinging Mean a Skincare Product Is Working?

min read: 8 mins

Can Oily Skin Have a Damaged Barrier?

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min read: 9 mins

What Does TEWL Actually Measure?

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min read: 4 mins

Why Does Azelaic Acid Sting?

min read: 9 mins

Does Skin Barrier Repair Take 28 Days?

min read: 9 mins

Can a Gentle Cleanser Still Disrupt the Skin Barrier?

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min read: 11 mins

Why Petrolatum Works: The Barrier Biology of Occlusion

min read: 7 mins

Drink More Water: Skincare’s Most Beloved Non-Answer

min read: 7 mins